Squamous Cell Esophageal Cancer: A Case Report


  • Almothana Aburumman Medicine




Squamous cell esophageal, esophageal cancer, dysphagia, metastasis, esophagogastroduodenoscopy biopsy


Esophageal cancer, particularly the squamous cell esophageal cancer, poses a substantial concern due to its late-stage presentations with unclear symptoms. Squamous cell cancer is characterized by squamous dysplasia, nuclear anaplasia, and the presence of keratinocyte-like cells with intercellular bridges or keratinization. Lesions might appear as ulcerative or diffusely infiltrative. This case report presents a 63-year-old male patient with significant past medical history who presented with chronic dysphagia as his chief complaint, and his recent esophagogastroduodenoscopy revealed a biopsy-proven 9cm hypermetabolic mid-esophageal tumor consistent with squamous cell esophageal carcinoma.


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Author Biography

Almothana Aburumman, Medicine

Orcid ID 0009-0007-0457-8124


Batra, R., Malhotra, G. K., Singh, S., & Are, C. (2019). Managing Squamous Cell Esophageal Cancer. Surgical Clinics of North America, 99(3), 529–541. https://doi.org/10.1016/j.suc.2019.02.006

Hou, W. H., Duan, X. K., Hou, W. D., Ma, L. J., Niu, J. W., Zhou, S. L., & Jin, M. L. (2021). [Clinicopathological features of basal cell type dysplasia of esophagus]. Zhonghua Bing Li Xue Za Zhi = Chinese Journal of Pathology, 50(6), 638–644. https://doi.org/10.3760/CMA.J.CN112151-20201009-00770

Kono, M., Kanesaka, T., Ishihara, R., Kitamura, M., Shoji, A., Inoue, T., Matsueda, K., Miyake, M., Waki, K., Shimamoto, Y., Fukuda, H., Iwagami, H., Matsuura, N., Nakahira, H., Shichijo, S., Maekawa, A., Yamamoto, S., Takeuchi, Y., Higashino, K., … Fujiwara, Y. (2021). Delineating the extent of esophageal squamous cell carcinoma. Esophagus, 18(4), 790–796. https://doi.org/10.1007/S10388-021-00854-W/METRICS

Minashi, K., Nihei, K., Mizusawa, J., Takizawa, K., Yano, T., Ezoe, Y., Tsuchida, T., Ono, H., Iizuka, T., Hanaoka, N., Oda, I., Morita, Y., Tajika, M., Fujiwara, J., Yamamoto, Y., Katada, C., Hori, S., Doyama, H., Oyama, T., … Muto, M. (2019). Efficacy of Endoscopic Resection and Selective Chemoradiotherapy for Stage I Esophageal Squamous Cell Carcinoma. Gastroenterology, 157(2), 382-390.e3. https://doi.org/10.1053/J.GASTRO.2019.04.017

Morgan, E., Soerjomataram, I., Rumgay, H., Coleman, H. G., Thrift, A. P., Vignat, J., Laversanne, M., Ferlay, J., & Arnold, M. (2022). The Global Landscape of Esophageal Squamous Cell Carcinoma and Esophageal Adenocarcinoma Incidence and Mortality in 2020 and Projections to 2040: New Estimates From GLOBOCAN 2020. Gastroenterology, 163(3), 649-658.e2. https://doi.org/10.1053/J.GASTRO.2022.05.054

Nakanishi, Y. (2020). Pathology of Esophageal Squamous Cell Carcinoma. Esophageal Squamous Cell Carcinoma, 15–34. https://doi.org/10.1007/978-981-15-4190-2_2

Savant, D., Zhang, Q., & Yang, Z. (2021). Squamous Neoplasia in the Esophagus. Archives of Pathology & Laboratory Medicine, 145(5), 554–561. https://doi.org/10.5858/ARPA.2020-0058-RA

Shiratori, Y., Kanomata, N., Takagi, K., & Fukuda, K. (2021). Esophageal basaloid squamous cell carcinoma presenting as a subepithelial lesion. Clinical Journal of Gastroenterology, 14(5), 1324–1328. https://doi.org/10.1007/S12328-021-01449-9/METRICS

Then, E. O., Lopez, M., Saleem, S., Gayam, V., Sunkara, T., Culliford, A., & Gaduputi, V. (2020). Esophageal Cancer: An Updated Surveillance Epidemiology and End Results Database Analysis. World Journal of Oncology, 11(2), 55. https://doi.org/10.14740/WJON1254

Uhlenhopp, D. J., Then, E. O., Sunkara, T., & Gaduputi, V. (2020). Epidemiology of esophageal cancer: update in global trends, etiology and risk factors. Clinical Journal of Gastroenterology, 13(6), 1010–1021. https://doi.org/10.1007/S12328-020-01237-X/METRICS

Weihua, H., Xinke, D., Weidong, H., Minqiang, S., Xiaolan, Z., Yanfeng, L., & Mulan, J. (2021). [Clinicopathological features of basal cell layer type high-grade squamous dysplasia of the esophagus]. Zhonghua Bing Li Xue Za Zhi = Chinese Journal of Pathology, 50(3), 236–241. https://doi.org/10.3760/CMA.J.CN112151-20200611-00465




How to Cite

Aburumman, A. (2024). Squamous Cell Esophageal Cancer: A Case Report. Journal of Social Sciences (COES&Amp;RJ-JSS), 13(3), 65–70. https://doi.org/10.25255/jss.2024.